引用本文:
【打印本页】   【HTML】   【下载PDF全文】   View/Add Comment  【EndNote】   【RefMan】   【BibTex】
←前一篇|后一篇→ 过刊浏览    高级检索
本文已被:浏览 732次   下载 376 本文二维码信息
码上扫一扫!
分享到: 微信 更多
Ester-Derivatized Indoles as Fluorescent and Infrared Probes for Hydration Environments
Xin-yue Huang1, Min You1, Guang-liu Ran1, Hao-ran Fan2, Wen-kai Zhang1
1.Department of Physics and Applied Optics Beijing Area Major Laboratory, Center for Advanced Quantum Studies, Beijing Normal University, Beijing 100875, China;2.Department of Chemistry, Beijing Normal University, Beijing 100875, China
Abstract:
Tryptophan derivatives have long been used as site-specific biological probes. 4-Cyanotryptophan emits in the visible region and is the smallest blue fluorescent amino acid probe for biological applications. Other indole or tryptophan analogs may emit at even longer wavelengths than 4-cyanotryptophan. We performed FTIR, UV-Vis, and steady-state and time-resolved fluorescence spectroscopy on six ester-derivatized indoles in different solvents. Methyl indole-4-carboxylate emits at 450 nm with a long fluorescence lifetime, and is a promising candidate for a fluorescent probe. The ester-derivatized indoles could be used as spectroscopic probes to study local protein environments. Our measurements provide a guide for choosing esterderivatized indoles to use in practice and data for computational modeling of the effect of substitution on the electronic transitions of indole.
Key words:  Infrared probe  Fluorescent probe  Tryptophan derivative  Indole derivative
FundProject:This work was supported by Beijing Natural Science Foundation (L172028), the National Natural Science Foundation of China (No.21773012 and No.91753118), the Recruitment Program of Global Youth Experts and the Fundamental Research Funds for Central Universities.
酯基取代的吲哚衍生物的红外和荧光光谱研究
黄心悦1, 游敏1, 冉光柳1, 范浩然2, 张文凯1
1.北京师范大学物理学系, 应用光学北京市重点实验室, 高等量子研究中心, 北京 100875;2.北京师范大学化学学院, 北京 100875
摘要:
关键词:  
DOI:10.1063/1674-0068/31/cjcp1805118
分类号: