| Abstract: |
| To enhance the binding ability of β-cyclodextrin with naphthalene derivatives，a hydrophobic group to the rim of β-cyclodextrin was added and the new β-cyclodextrin compound—mono-6-p-nitrobenzoyl-β-cyclodextrin was synthesized. Its binding ability for 1: 1 inclusion complexation with 1-naphthoic acid was evaluated in the KCl/HCl buffer solution（pH=1.5，0.1 mol/dm3）at 15℃ by the spectrofluormetric titration. The results obtained indicated that mono-6-p-nitrobenzoyl-β-cyclodextrin could strongly include 1-naphthoic acid in aqueous solution；the modification dramatically enhanced the original binding ability of native β-cyclodextrin by a factor 9. The binding constants of mono-6-p-nitrobenzoyl-β-cyclodextrin and other naphthalenes such as 1-methoxynaphthalene，2-methoxynaphthalene，1-N，N-dimethylaminonaphthalene and 1-N，N-dimethylaminonaphthalene were obtained from the time-resolved fluorescence. The high binging ability of naphthalenes with NBCD make it is possible to assemble stable host-guest complexes. |
| Key words: Binding ability,β-cyclodextrin,Naphthalene derivatives,Fluorescence spectroscopy |
| FundProject: |
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| 单-6-氧-（对硝基苯甲酰基）-β-环糊精与萘衍生物包合作用的荧光光谱研究 |
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王永辉1, 朱满洲1, 叶建平2, 郭庆祥*1
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1.中国科学技术大学化学系，合肥 230026;2.中国科学院化学研究所，北京 100080
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| 摘要: |
| 合成了一种新的环糊精衍生物单-6-氧-（ 对硝基苯甲酰基）-β-环糊精（NBCD）. 该化合物与1-萘甲酸（NA）在KCl/HCl缓冲水溶液（pH=1.5，0.1 mol/dm3）中形成1: 1包合物，15℃时的包合常数由稳态荧光测定，结果表明，NBCD 可以和1-萘甲酸形成稳定的包合物，与β-环糊精相比，稳定常数增加9 倍左右. 同时，时间分辨荧光得到了NBCD 与其它给电子的萘的衍生物的包合常数. 结果表明，在β-环糊精的6 位引进对硝基苯甲酰基能够显著增强其包合能力，使NBCD能够与萘的衍生物形成稳 |
| 关键词: 包合能力 环糊精 萘衍生物 荧光光谱 |
| DOI：10.1088/1674-0068/17/1/56-60 |
| 分类号: |
