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Converting Molecular Vibration to Mechanical Wave for Bond-Selective Imaging of Deep Tissue (cited: 1)
Jie Hui1, Ji-xin Cheng*2,3
1.Department of Physics and Astronomy, Purdue University, West Lafayette, Indiana 47907, USA;2.Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 47907, USA;3.Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA
Abstract:
As an emerging label-free imaging modality with chemical selectivity and millimeter-depth resolvability, vibrational photoacoustic imaging provides a new avenue to map chemical content in biological tissue. It heralds the potential for detection of white matter loss and regeneration, assessment of breast tumor margin, and clinical diagnosis of vulnerable plaques in atherosclerosis. In this work, we provide an overview of the development of bond-selective photoacoustic imaging and various biomedical applications enabled by this new technology.
Key words:  Label-free, Vibrational spectroscopy, Chemical imaging
FundProject:
基于光声效应的深层组织选键成像 (cited: 1)
惠杰,程继新*
1.美国普渡大学物理系,印第安纳州;2.美国普渡大学生物医学工程系及化学系,印第安纳州
摘要:
基于分子振动吸收的光声成像技术为生物组织的化学成像提供了一个新的平台.该技术在脊髓损伤、肿瘤、及心血管疾病的检测方面有广泛的应用前景.本文综述该技术的发展历史及其在生物医学中的应用.
关键词:  非标记检测,振动光谱,化学成像
DOI:10.1063/1674-0068/28/cjcp1504069
分类号: