Study of the Light Sensitivity of Podophyllotoxin and Its Derivatives
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Abstract
Podophyllotoxin and its derivatives are very light (UV) sensitive, and can be readily photo-ionized to produce some transient species. The laser flash photolysis of podophyllotoxin and its derivatives has been performed for the first time. The mechanism of photo-ionization has been confirmed and illustrated. In addition, the pKa and the molar extinction coffients of the transientn species have been determined.
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