Surface-Enhanced Raman Spectroscopy of Uracil and 5-halide Uracils Adsorbed by Silver Hydrosols

This is the first reporting article in our serial researching of the bases which are the components of nucleic acids. Normal Raman and surface-enhanced Raman Scattering Spectroscopy of uracil and 5-halide uracils have been obtained and compared. When the 5-H was replaced with halide atoms. the frequency and relative strength of related atoms' vibration changed. It was found that the adsorption active site of molecule changed with the change of substituting halide atoms. Uracil adsorbed on the surface of silver hydrosols with 1-N; 5-fluoro uracil and 5-chloro uracil adsorbed partly with 1-N, partly with 5-halide atoms; and 5-bromo uracil adsorbed with 5-Br completely. This change coincided with the change of chelating ability of N→Ag, F→Ag, Cl→Ag, and Br→Ag.