Mophology Character of the Sol-gel Derived Bioactive Glass in SBF Solution
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Graphical Abstract
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Abstract
The sol-gel derived bioactive glass in the system CaO-P2O5 -SiO2 was prepared using sol-gel technology and the porous bioactive material as bone defects filler and bone tissue engineering scaffold was made from the solgel bioactive glass powder through sintering. The crystalline phases,microstructure and bioactiviity of the sintered porous material was investigated using XRD、SEM and FTIR techniques and in vitro method. It was indicated that a few Ca5(PO4)2SiO4 ( 5CPS)crystals had been formed in the porous material during sintering at 800℃ for 5 min. In the simulated body fluid(SBF),as the reaction progressed,the originally formed amorphous-phosphorus compound on the surface of glass mineralized hydroxy-carbonate-apatite(HCA)nanometer cluster,and interfused mutually until the HCA covering was formed. HCA crystallites only formed on the glass-phase. No HCA crystal was formed on the surface of 5CPS.
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