H/D Exchange Reaction of Cyclopropane Derivatives in the Ion System of D2O

H/D exchange reaction properties of four cyclopropane derivatives were examined using D2O as reaction reagent under chemical ionization condition. The fragmentation properties of the product ions M+1+, M+2+ and M+3+ formed by ion-molecule reaction of four cyclopropane derivatives with the ion system of CD3OD were investigated by using collision-induced dissociation technique. The experimeat results indicate that the product ions are produced via the H/D exchange reaction between reactants and reactive reagent ions of CD3OD. The exchangeable hydrogen on the ring carbon bearing the isobutenyl (or dichloroethylene) groups is more active than that on the ring carbon bearing carbonyl group.